| ORIGINAL ARTICLE |
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| Year : 2021 | Volume
: 18
| Issue : 1 | Page : 14-21 |
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Association of total lymphocyte count and echocardiographic parameters in human immunodeficiency virus-positive patients
Abaram Chesa Mankwe1, Jonah Sydney Aprioku2
1 Cardiology Unit, Department of Internal Medicine, Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria
2 Department of Experimental Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Port Harcourt, Nigeria
Correspondence Address:
Dr. Abaram Chesa Mankwe
Cardiology Unit, Department of Internal Medicine, Federal Medical Centre, Yenagoa, Bayelsa State
Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/njc.njc_38_20
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Background: The pathophysiology of cardiovascular diseases in HIV infection has been linked to chronic inflammation that precipitates atherosclerosis and low lymphocyte count is a common finding during the systemic inflammatory response.
Aim: The aim of this study is to evaluate the relationship between total lymphocyte count (TLC) and echocardiographic parameters in HIV positive subjects.
Method: TLC of 100 HAART naïve newly diagnosed HIV/AIDS subjects, recruited from a Nigerian Tertiary Health Institution were analyzed, and their left ventricular (LV) function and geometry were evaluated using transthoracic echocardiography.
Results: Abnormalities in LV function and geometry were observed in the HIV seropositive subjects and their TLCs were lower in those with severe forms of abnormalities.
Conclusion: Concluding, TLC is inversely associated with LV dysfunction or abnormal geometry.
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