Nigerian Journal of Cardiology

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 18  |  Issue : 1  |  Page : 14--21

Association of total lymphocyte count and echocardiographic parameters in human immunodeficiency virus-positive patients


Abaram Chesa Mankwe1, Jonah Sydney Aprioku2 
1 Cardiology Unit, Department of Internal Medicine, Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria
2 Department of Experimental Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Port Harcourt, Nigeria

Correspondence Address:
Dr. Abaram Chesa Mankwe
Cardiology Unit, Department of Internal Medicine, Federal Medical Centre, Yenagoa, Bayelsa State
Nigeria

Background: The pathophysiology of cardiovascular diseases in HIV infection has been linked to chronic inflammation that precipitates atherosclerosis and low lymphocyte count is a common finding during the systemic inflammatory response. Aim: The aim of this study is to evaluate the relationship between total lymphocyte count (TLC) and echocardiographic parameters in HIV positive subjects. Method: TLC of 100 HAART naïve newly diagnosed HIV/AIDS subjects, recruited from a Nigerian Tertiary Health Institution were analyzed, and their left ventricular (LV) function and geometry were evaluated using transthoracic echocardiography. Results: Abnormalities in LV function and geometry were observed in the HIV seropositive subjects and their TLCs were lower in those with severe forms of abnormalities. Conclusion: Concluding, TLC is inversely associated with LV dysfunction or abnormal geometry.


How to cite this article:
Mankwe AC, Aprioku JS. Association of total lymphocyte count and echocardiographic parameters in human immunodeficiency virus-positive patients.Nig J Cardiol 2021;18:14-21


How to cite this URL:
Mankwe AC, Aprioku JS. Association of total lymphocyte count and echocardiographic parameters in human immunodeficiency virus-positive patients. Nig J Cardiol [serial online] 2021 [cited 2022 Oct 4 ];18:14-21
Available from: https://www.nigjcardiol.org/article.asp?issn=0189-7969;year=2021;volume=18;issue=1;spage=14;epage=21;aulast=Mankwe;type=0